Gluten Sensitivity Without Celiac Disease?
A gluten-free diet might benefit selected patients with irritable bowel syndrome.
Some patients with symptoms of irritable bowel syndrome (IBS), but no evidence of celiac disease, report gluten sensitivity. To determine whether these observations hold up under double-blind, placebo-controlled conditions, Australian researchers enrolled 34 adults in whom celiac disease had been ruled out by standard criteria but who reported intolerance to gluten-containing products.
They all followed their typical gluten-free diets and, additionally, were randomised to receive either gluten-containing or gluten-free (placebo) bread and muffins daily for 6 weeks. The proportion of patients who reported inadequate control of overall symptoms was significantly higher in the gluten group than in the placebo group (68% vs. 40%). Several specific symptoms (abdominal pain, tiredness, dissatisfaction with stool consistency, and bloating) also were significantly more prominent in the gluten group. No differences in markers of inflammation in blood or stool were noted between groups.
Comment: This study suggests that gluten can trigger irritable bowel symptoms –– via unknown mechanisms –– in some people who exhibit no evidence of celiac disease. A therapeutic trial of a gluten-free diet might be worthwhile for selected patients with IBS.
Biesiekierski JR et al. Gluten causes gastrointestinal symptoms in subjects without celiac disease: A double-blind randomised placebo-controlled trial. Am J Gastroenterol 2011 Mar; 106:508. (http://dx.doi.org/10.1038/ajg.2010.487)
Panaxea - World Medicine.
Clinical experience has shown that a gluten free diet can benefit other patients with other types of complaints.
It is difficult to asses if the health improvements are due to an overall improved diet and less consumption of refined foods, or it is due to the avoidance of gluten.
It is worthwhile the experiment.
Are you following a gluten free diet? Remember that gluten free products are often laden with bad fats, can be highly refined and not healthy at all.
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